Recent Publications

Clara Abraham

• Hedl M, Li J, Cho JH, and Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. PNAS. Epub Nov 21, 2007.
• Marski M, Ye AL, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints. J Immunol. 178:2104-2112, 2007.
• Abraham C and Cho JH. Bugging of the intestinal mucosa. N Engl J Med. 357:708-710, 2007.

Harry Aslanian

• Aslanian, H. “EUS Guided FNA of a Liver Mass”. The DAVE Project. 12 Dec 2006. Jan 8, 2007 (peer reviewed, online video atlas).
• Savides TJ, Donohue M, Hunt G, Al-Haddad M, Aslanian H, Ben-Menachem T, Chen VK, Coyle W, Deutsch J, DeWitt J, Dhawan M, Eckardt A, Eloubeidi M, Esker A, Gordon SR, Gress F, Ikenberry S, Joyce AM, Klapman J, Lo S, Maluf-Filho F, Nickl N, Singh V, Wills J, Behling C. EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. Gastrointest Endosc 2007;66:277-8.
• Rogart J., Greenwald A., Rossi F., Barrett P., Aslanian H. Aortoesophageal fistula following polyflex stent placement for refractory benign esophageal stricture. Endoscopy (in press).
• Rossi, F., Sosa, JA., Aslanian, HR. Screening colonoscopy and fecal occult blood testing practice patterns: a population based survey of gastroenterologists. Journal of Clinical Gastroenterology (in press).

Henry Binder

• Jiang, Z, Asplin, JR, Evan AP, Rajendran VM, Velazquez, H, Nottoli, TP, Binder, HJ and Aronson PS: Calcium oxylate urolithiasis in mice lacking anion transporter Slc26a6. Nat. Genet. 38:474-478, 2006.
• Raghupathy, P, Ramakrishna, BS, Oommen, SP, Ahmed, MS, Priyaa, G, Dziura, J, Young, GP, Binder, HJ: Amylase-resistant starch as adjunct to oral rehydration therapy in children with diarrhea. J. Ped. Gastro. Nutr. 42:362-368, 2006.
• Subramanya, S, Balakrishnan, BS, Ramakrishna, S, Young, GP, Binder, HJ: Evaluation of oral rehydration solution by whole gut perfusion in rats: effects of osmolarity, sodium concentration and resistant starch. J. Ped. Gastro. Nutr. 2006 Nov;43(5):568-75.
• Characteristics of rat downregulated in adenoma (rDRA) expressed in HEK 293 cells. Pflugers Arch. 2007 Jun;454(3):441-50. Epub 2007 Feb 16.
• Differential Regulation of Cholera Toxin-Inhibited Na-H exchange Isoforms by Butyrate in Rat Ileum. Am J Physiol Gastrointest Liver Physiol. 2007 Aug 9; [Epub ahead of print].

James Boyer

• Ballatori N, Henson JH, Seward DJ, Cai S-Y, Runnegar M, Fricker G, Miller DS and Boyer JL. Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comp Biochem Physiol B Biochem Mol Biol. 2006 Jun;144(2):167-79
• Mennone, A, Soroka, CJ, Cai, S-Y, Harry, K, Adachi, M, Hagey, L, Schuetz, J and Boyer, JL. Mrp4 -/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology. 2006 May;43(5):1013-21
• Denk, GU, Shi-Ying Cai, Wen-Sheng Chen, Aiping Lin, Carol J.Soroka, James L. Boyer. A comparison of gene expression in mouse liver and kidney in obstructive cholestasis utilizing high-density oligonucleotide microarray technology. World J Gastroenterol. 2006 Apr 28;12(16):2536-48.
• Boyer, JL, Trauner, M, Mennone, A, Soroka, CJ, Cai, S-Y, Moustafa, T, Zollner, G, Lee, JY and Ballatori, N. Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OST -OSTß, in cholestasis in humans and rodents. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1124-30.
• Wang, W, Soroka, CJ, Mennone, A, Rahner, C, Harry, K, Pypaert, M and Boyer, JL. Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Gastroenterology. 131:878-884,2006
• Villanueva SS, Ruiz ML, Soroka CJ, Cai SY, Luquita MG, Torres AM, Sanchez Pozzi EJ, Pellegrino JM, Boyer JL, Catania VA, Mottino AD. Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats. Drug Metab Dispos 34:1301-1309,2006.
• Tradtrantip L, Boyer JL, Suksamrarn A, PIyachaturawat P. Differential effects of hydroxyacetophenone analogues on the transcytotic vesicular pathway in rat liver. Eur. J. Phrm 547:152-159,2006.
• Meier-Abt F, Hammann-Hanni A, Stieger B, Ballatori N and Boyer JL. The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver. Tox. Appl. Pharm. 218:274-279,2007.
• Chen, W. Cai, SY, Xu, S, Denson, L, Soroka, C, Boyer, J. Nuclear Receptors RXR :RAR are Repressors for Human MRP3 Expression, Am J Physiol Gastrointest Liver Physiol. 292(5):G1221-7,2007.
• Tradtrantip,L, Piyachaturawat, P, Soroka, C, Harry, K, Mennone, A, Mahagita, C, Ballatori, N, and Boyer, JL Phloracetophenone-Induced Choleresis in Rat is Mediated Through Mrp2. Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G66-74
• Cai SY, Xiong L, Wray CG, Ballatori N, Boyer JL. The farnesoid X receptor, FXR{alpha}/NR1H4, acquired ligand specificity for bile salts late in vertebrate evolution. Am J Physiol Regul Integr Comp Physiol.. 293(3):R1400-9, 2007
• Sun AQ, Ponamgi VM, Boyer JL, Suchy FJ. Membrane Trafficking of the Human OrganicAnion-Transporting Polypeptide C (hOATPC). Pharm Res. 2007 Jul 20; [Epub ahead of print]
• Lam P, Pearson CL, Soroka C, Xu S, Mennone A, Boyer JL. The Level of Plasma Membrane Expression in Progressive and Benign Mutations of the Bile Salt Export Pump (Bsep/Abcb11) Correlate with Severity of Cholestatic Diseases. Am J Physiol Cell Physiol. 2007 Sep 13; [Epub ahead of print]

Judy H. Cho

• Rioux JD, Xavier R, Taylor KD, Goyette P, Green T, Huett A, Kuballa P, Mei L, Regueiro M, Rotter JI, Steinhart H, Schumm LP, Barmada MM, Shugart YY, Nicolae DL, Silverberg MS, Cho JH, Daly MJ, Brant SR. Identification of novel susceptibility genes for Crohn's disease implicates a crucial role for autophagy. , equal contributions. Nature Genetics April 15, 2007
• Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee A, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH. A genome-wide association study identified IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-3.
• Gewirtz AT, Vijay-Kumar M, Brant SR, Duerr RH, Nicolae DL, Cho JH. Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2006; 290: G1157-1163.

Chuhan Chung

• Chung C, Doll JA, Stellmach VM, Gonzales J,Surapureddi S, Cornwell M, Reddy JK, Crawford SE. Pigment Epithelium-Derived Factor (PEDF) is an Angiogenesis and Lipid Regulator that Activates Peroxisome Proliferator-Activated Receptor _ (PPAR_). In: Hormonal Carcinogenesis 5th Edition. Springer-Verlag Press, 2007
• Browne MB, Stellmach V, Cornwell M, Chung C, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE. Gene Transfer of Pigment Epithelium-Derived Factor Suppresses Tumor Growth and Angiogenesis in a Hepatoblastoma Xenograft Model. Pediatr Res 2006;60:282-287.
• Chung C, Stellmach V, Cornwell M, Doll J, Crawford SE. Loss of Pigment Epithelium-Derived Factor Promotes Hepatocellular Lipid Accumulation. (submitted)

Jon Dranoff

• Kruglov EA, Correa PR, Arora G, Yu J, Nathanson MH, Dranoff JA. Molecular basis for calcium signaling in hepatic stellate cells. Am. J. Physiol. 292:G975 (2007).
• Kruglov EA, Nathanson RA, Nguyen T, Dranoff JA. Secretion of MCP-1/CCL2 by bile duct epithelia induces myofibrobastic transdifferentiation of portal fibroblasts. Am. J. Physiol. 290:G765 (2006).
• Jhandier MN, Kruglov EA, Lavoie EG, Sevigny J, Dranoff JA. Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. J. Biol. Chem. 280:22986 (2005).

Martin Floch

• Floch, MH, Madsen KK, Jenkins DJ, Guandalini S, Katz JA, Onderdonk A, Walker WA, Fedorak RN, Camillieri M. Recommendations for probiotic use. J Clin Gastroenterol 2006;40(3):275-8
• Siewert JR, Giuli R, Floch MH. OESO and the Journal of Clinical Gastroenterology. J Clin Gastroenterol 2006;40(5):373
• Floch, MH. A hypothesis: is diverticulitis a type of inflammatory bowel disease? J Clin Gastroenterol 2006;40(7 Suppl 3):S121-5
• Floch, MH, White JA. Management of diverticular disease is changing. World J Gastroenterol 2006 May 28;12(20): 3225-3228
• Floch, MH. Report on 8th World Congress of OESO. J Clin Gastroenterol 2007;41(2):121-2
• Park J, Floch MH. Prebiotics, Probiotics, and Dietary Fiber in Gastrointestinal Disease. In: Gastroenterology Clinics of North America. Philadelphia, PA. Elsevier March 2007;36(1):47-63
• Binder JH, Floch MH. Enteric Flora in Health and Disease. J Clin Gastroenterol 2007;41(Suppl 1):S1

Guadalupe Garcia-Tsao

• Longacre AV, Garcia-Tsao G. A commonsense approach to esophageal varices. Clin Liver Dis 2006;10:613-625.
• Ghassemi S, Garcia-Tsao G. Prevention and treatment of infections in patients with cirrhosis. Best Pract Res Clin Gastroenterol. 2007;21(1):77-93.
• Garcia-Tsao G. Liver involvement in hereditary hemorrhagic telangiectasia (HHT). J Hepatol. 2007 Mar;46(3):499-507.

Sahar Ghassemi

• Ghassemi S, Garcia L. Prevention and Treatment of Infections in Patients with Cirrhosis. Best Practice and Research Clinical Gastroenterology. 21( 1) 77-93 2007.
• (Ghassemi, S., Garcia L. Management of Cirrhosis in Patients Awaiting Liver Transplantation. Liver Transplantation for Non-Specialists. Permanyer Publications.13-33. 2006 (textbook chapter)
• Ghassemi S. Gastrointestinal and Liver complications in the Cancer Survivor. (textbook chapter) 2007 (in press)

Fred Gorelick

• S. Husain, T. Kolodecik, M. Nathanson, F. Gorelick. Regulation of zymogen processing in acinar cells by the ryanodine receptor. Proc Natl Acad Sci, USA. 2005 102:14386-91.
• Thrower, A. Devilla-Villa, T. Kolodecik and F. Gorelick. Zymogen activation in a reconstituted pancreatic acinar cell system. Am J Physiol Gastrointest Liver Physiol. 2006 290(5):G894-90.
• Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proc Natl Acad Sci U S A. 2006 103:1941-6.
• Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster Proc Natl Acad Sci U S A. 2006 103:1936-40.
• Otani T, Matsukura A, Takamoto T, Seyama Y, Shimizu Y, Shinomiya M, Usui H, Gorelick FS, Makuuchi M. Effects of pancreatic duct ligation on pancreatic response to bombesin. Am J Physiol Gastrointest Liver Physiol. 2006 290(4):G633-9.
• Siddiqi SA, Siddiqi S, Mahan J, Peggs K, Gorelick FS, Mansbach CM. The identification of a novel ER to Golgi SNARE complex used by the Pre-chylomicron transport vesicle.J Biol Chem. 2006 281(30):20974-82.
• Siddiqi SA, Mahan J, Siddiqi S, Gorelick FS, Mansbach CM 2nd. Vesicle-associated membrane protein 7 is expressed in intestinal ER.J Cell Sci. 2006 119:943-50.
• Chaudhuri A, Husain SZ, Kolodecik TR, Grant WM, Gorelick F. Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.Am J Physiol Gastrointest Liver Physiol. 2007 292: G1403-G1410.
• Husain SZ, Grant WM, Gorelick F, Nathanson MH, Shah AU. Caerulein-induced Intracellular Pancreatic Zymogen Activation is Dependent upon Calcineurin. Am J Physiol Gastrointest Liver Physiol. 2007 292: G1594-9.

Roberto Groszmann

• Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G. Histological hemodynamic correlation in cirrhosis – a histological classification of the severity of cirrhosis. J Hepatol 2006 Jan;44(1):111-117.
• Yasuko Iwakiri and Roberto J Groszmann. The Hyperdynamic Circulation of Chronic Liver Diseases: From the Patient to the Molecule. Hepatology (Special Anniversary Issue) 43(S1); S121-S131, 2006.
• Mauricio Silva, Yasuko Iwakiri, Juan G Abraldes, Omar Haq and Roberto J Groszmann. Increased phosphodiesterase-5 expression is involved in the decreased vasodilator response to nitric oxide in cirrhotic rat livers. J Hepatology 44(5):886-893, 2006.
• Juan G. Abraldes, Yasuko Iwakiri, Mauricio Loureiro-Silva, Omar Haq, William C. Sessa, and Roberto J. Groszmann. Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed leading to a hyperdynamic state. American Journal of Physiology: Gastrointestinal and Liver Physiology 290: G980-G987, 2006.
• Shneider B, Emre S, Groszmann R, Karani J, McKiernan P, Sarin S, Shashidhar H, Squires R, Superina R, de Ville de Goyet J, deFranchis R. Portal hypertension in children: Expert pediatric opinion on the report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension. Pediatr. Transplantation. 10:893-907, 2006.
• Yasuko Iwakiri, Ayano Satoh, Subro Chatterjee, Vijay Shah, Cecile Chalouni, Derek Toomre, David Fulton, Roberto J. Groszmann, and William C. Sessa. Nitric Oxide Synthase Generates Nitric Oxide Locally to Regulate Compartmentalized Protein S-nitrosylation and Protein Trafficking. Proc Natl Acad Sci USA Dec 14;103(52):19777-82. 2006.
• Kwon SY, Groszmann RJ, Iwakiri Y. Increased neuronal nitric oxie synthase interaction with soluble guanylate cyclase contributes to the splanchnic arterial vasodilation in portal hypertensive rats. Hepatol Res Jan;37(1):58-67, 2007.
• Joe Lim and Roberto Groszmann. Transient Elastography for Diagnosis of Portal Hypertension in Liver Cirrhosis: Is There Still a Role for HVPG Measurement? Editorial Hepatology 45(5); 1087-1090, 2007.
• Yasuko Iwakiri and Roberto J Groszmann. Vascular endothelial dysfunction in cirrhosis. Review J Hepatology 46(5); 927-934, 2007.
• Cristina Ripoll, Roberto Groszmann, Guadalupe Garcia-Tsao, Norman Grace, Andrew Burrougghs, Juan Carlos Garcia-Pagan, Ramon Planas, Angels Escorsell, Robert Makuch, David Patch, Daniel S. Matloff and Jaime Bosch for the Portal Hypertension Collaborative Group. Hepatic Venous Pressure Gradient Predicts Clinical Decompensation in Patients with Compensated Cirrhosis. Gastroenterology Aug 133(2):481-488; 2007.

Avlin Imaeda

• Imaeda, A., Sutterwala, F., Watanabe, A., Mahmood, S., Sohail, M., Flavell, R., Mehal, W. (2007, manuscript submitted) Acetaminophen induced hepatotoxicity is dependent on the NALP3 inflammasome and can be inhibited by aspirin.
• Longacre, A., Imaeda, A., Garcia-Tsao, G., Fraenkel, L. (2007) A pilot project examining the predicted preferences of patients an dphysicians in the primary prophylaxis of variceal hemorrhage. Hepatology (published online Oct 12)
• Rodes, J., Benhamou, J-P., Blei, A., Reichen, J., Rizzetto, M. ed Textbook of Hepatology. Blackwell Publishing (2007). “Chap 2.7.3 Antibody Production and Transport in the Liver.” Imaeda, A, Mehal, W. pp325-332

Yasuko Iwakiri

• Soyoung Kwon, Roberto J Groszmann, and Yasuko Iwakiri. Increased Neuronal Nitric Oxide Synthase Interaction with Soluble Guanylate Cyclase Contributes to the Splanchnic Arterial Vasodilation in Portal Hypertensive Rats. Hepatology Research. 2007. 37(1): 58-67.
• Yasuko Iwakiri and Roberto J Groszmann. Vascular Endothelial Dysfunction in Cirrhosis. Journal of Hepatology. 2007. 46(5): 927-934.
• Yasuko Iwakiri, Ayano Satoh, Suvro Chatterjee, Vijay Shah, Cecile Chalouni, Derek Toomre, David Fulton, Roberto J Groszmann, and William C. Sessa. Nitric Oxide Synthase Generates Nitric Oxide Locally to Regulate Compartmentalized Protein S-nitrosylation and Protein Trafficking. Proc, Natl Acad Sci USA. 2006. 103(52): 19777-82.

Dhanpat Jain

• Marginean EC, M Bennick M, Cycyzk J, Robert ME, Jain D. Gastric Glandular Siderosis: Patterns and significance. Am J Surg Pathol, 30:514-520, 2006.
• Nagula S, Jain D, Groszmann RJ, Garcia-Tsao L. Histological-hemodynamic correlation in cirrhosis – A histological classification of the severity of cirrhosis. J Hepatology, 44;111-117, 2006.
• Jain D, Fatima Eslami-Varzaneh,MD* ; Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite Glandular and Endocrine Tumors of the Stomach with Pancreatic Acinar Differentiation. Am J Surg Pathol, 2005, 29:1524-29.

Priya Jamidar

• Vignesh S, Jamidar P. EUS-guided pancreatogastrostomy and pancreatobulbostomy in patients with pancreatic-duct obstruction inaccessible to transpapillary endoscopic therapy: working our way to NOTES. Gastrointest Endosc. 2007 Feb;65(2):242-6.
• Muralidharan V, Jamidar P. Pharmacologic prevention of post-ERCP pancreatitis: is nitroglycerin a sangreal?
• Gastrointest Endosc. 2006 Sep;64(3):358-60. Epub 2006 May 19 Siddiqui U, Jamidar P. Endoscopic Therapy for the Treatment of Pain in Chronic Pancreatitis: A Success Story in Tropical Pancreatitis. (In Press)

Caroline Loeser

• Rogart JN, Nagata J, Loeser C, Roorda RD, Aslanian H, Robert ME, Zipfel WR, Nathanson MH. Multiphoton imaging can be used for microscopic examination of intact human gastrointestinal mucosa. Clinical Gastroenterology and Hepatology in press.

Wajahat Mehal

• Lakhani1 SA, Masud1 A, Kuida K, Porter Jr GA, Booth CJ, Mehal WZ, Inayat I, Flavell RA. Caspases 3 and 7: Key Mediators of Mitochon Events of Apoptosis Science. 2006; 311(5762): 847-51.
• Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, and Flavell RA. Modulation of Cell Adhesion and Motility in the Immune System by Myo1f. Science 6, 2006: 136-139
• Badu A, Jha MK, Matza D, Mehal WZ, Freichel M, Flockerzi V, Flavell RA. Critical role for the regulatory subunits of Cav channels in T lymphocyte function. PNAS. 103(42):15529-34, 2006.
• Qamar A, Sheikh SZ, Masud A, Jhandier MN, Inayat IB, Hakim W, Mehal W. In-vitro and In-vivo Protection of Stellate Cells From Apoptosis by Leptin. Digestive Diseases and Sciences. 51(10):1697-705, 2006.
• Hashmi A, Hakim H, Kruglov E, Watanabe A, Watkins W, Dranoff JA,. Mehal WZ. Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells. American Journal of Physiology. 292(1):G395-401, 2007.
• Azuma Watanabe, Ardeshir Hashmi, Wyel Hakim, Dawidson Gomes, Wajahat Mehal DNA from Apoptotic Hepatocytes Induces HSC Differentiation and Inhibits Chemotaxis via TLR9. Hepatology. In Press
• Wyel Hakim, Shehzad Sheikh, Irteza Inayat, Margaret Bia, Cary Caldwell, Dhanpat Jain, Douglas Smith, Amy Friedman, Marc Lorber, Richard Formica, Wajahat Mehal. Pilot study of HCV Response in Patients with End Stage Renal Disease treated with Combination Pegylated Interferon a-2a and Ribavirin. Nephrology Dialysis Transplantation Submitted.
• Mehal WZ. Activation induced cell death (AICD) of hepatic stellate cells. In press with Gastroenterology for Feb 2006.
• Imaeda A., Mehal WZ. The humoral immune response in the liver. 3rd edition of Textbook of Hepatology: From Basic Science to Clinical Practice. Blackwell Publishers, Oxford England.
• Mehal WZ. Intrahepatic lymphocytes. 3rd edition of Textbook of Hepatology: From Basic Science to Clinical Practice. Blackwell Publishers, Oxford England.

Anil Bernard Nagar

• Wang S, Fadre O, Nagar A, Shafi N, Rose M. The diagnostic role of gastrointestinal endoscopy in anemic patients with a low normal ferritin level. Am. J. Hematology. 2006;81:324-327
• AGA Gastroenterlogy Teaching project. Pancreatic Physiology and Pancreatitis 2006. Senior Author Fred Gorelick. Co-authors Anil Nagar, Lars Fisher, Mark Topazian, Guillermo Robles-Diaz, Akihiko Sato and Stephen Pandol.
• Anil B. Nagar. Biliary Strictures in Pancreatic Disease. Techniques in Gastrointestinal Endoscopy, 2002, 3:113-119

Michael Nathanson

• O’Brien, E.M., Gomes, D.A., Sehgal, S., and Nathanson, M.H.: Hormonal regulation of nuclear permeability. J. Biol. Chem. 282:4210-4217, 2007.
• Hernandez, E., Leite, M.F., Guerra, M.T., Kruglov, E.A., Bruna-Romero, O., Rodrigues, M.A., Gomes, D.A., Giordano, F.J., Dranoff, J.A., and Nathanson, M.H.: The spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves. J. Biol. Chem. 282:10057-10067, 2007.
• Kruglov, E.A., Correa, P.R.A.V., Arora, G., Yu, J., Nathanson, M.H., and Dranoff, J.A.: Molecular basis for calcium signaling in hepatic stellate cells. Amer. J. Physiol. 292:G975-G982, 2007.
• Husain, S.Z., Grant, W., Gorelick, F.S., Nathanson, M.H., and Shah, A.: Caerulein-induced Intracellular Pancreatic Zymogen Activation is Dependent upon Calcineurin. Amer. J. Physiol. 292:G1594-G1599, 2007.
• Rodrigues, M.A., Gomes, D.A., Grant, W., Leite, M.F., Bennett, A.M., Zhang, L., Lam, W., Cheng, Y.-C., and Nathanson, M.H.: Nucleoplasmic calcium regulates cell growth. J. Biol. Chem. 282:17061-17068, 2007.
• Correa, P.R.A.V., Kruglov, E.A., Thompson, M., Leite, M.F., Dranoff, J.A., and Nathanson, M.H.: Succinate is a paracrine signal for liver damage. J. Hepatol. 47:262-269, 2007.
• Nagata, J., Guerra, M.T., Shugrue, C.A., Gomes, D.A., and Nathanson, M.H.: Lipid rafts establish calcium waves in hepatocytes. Gastroenterology 133:256-267, 2007.
• Minagawa, N., Nagata, J., Shibao, K., Masyuk, A.I., Gomes, D.A., Kaunitz, J.D., LeSage, G., Ehrlich, B.E., LaRusso, N.F., and Nathanson, M.H.: Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology, in press.
• Rogart, J.N., Nagata, J., Loeser, C.S., Roorda, R.D., Aslanian, H., Robert, M.E., Zipfel, W.R., and Nathanson, M.H.: Multiphoton imaging can be used for microscopic examination of intact gastrointestinal mucosa. Clinical Gastroenterology and Hepatology, in press.

Deborah Proctor

• Niederle M, Proctor DD, Roth AE. Resolution regarding gastroenterology fellowship applicants, including all research and clinical fellowship applicants and positions. (March 24, 2006).
• Niederle M, Proctor DD, Roth AE. What will be needed for the new gastroenterology fellowship match to succeed? Gastroenterology 2006;130(1):218-224.
• Hall KE, Proctor DD, Fisher L, Rose S. Effects of aging of the population. (Letter response) Gastroenterology 2006;130:1371-1372.
• Gross CP, Andersen MS, Krumholz HM, McAvay GJ, Proctor DD, Tinetti ME. The relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer. JAMA 2006;296:2815-2822.
• Rockey DC, Harrison SA, Wong RKH, Schiller LR, Proctor DD, Wolfe MM, Chutkan R, Vargo JJ, Waxler A. The gastroenterology core curriculum, third edition – May 2007. Gastroenterology 2007;132(5):2012-2018.
• Proctor DD, Henderson KJ, Dziura JD, White RI. Hormonal therapy for the treatment of gastrointestinal bleeding in hereditary hemorrhagic telangiectasia. J Clin Gastroenterology 2007.
• Siddiqui U, Proctor DD. Flexible sigmoidoscopy and colonoscopy during pregnancy. Gastrointestinal Endoscopy Clinics of North America 2006;16(1):59-69.
• Loeser CS, Proctor DD. Critical issues in digestive diseases: Gastrointestinal hemorrhage. Pulmonary and Critical Care Update 2006;20:Lesson 8. (March 31, 2006).
• Nagar AB, Proctor DD. Ulcers of the small and large intestine. Eds. Feldman, Friedman, and Brandt: Sleisenger & Fordtran’s Gastrointestinal and Liver Disease, 8th edition, 2006; pp. 2587-2597. Saunders Elsevier, Philadelphia, PA.
• Proctor DD. Approach to the patient with gastrointestinal disease. Eds. Goldman L and Ausiello DA. Cecil Textbook of Medicine, 23rd edition, 2007; pp. 951-965. Saunders Elsevier Inc., Philadelphia, PA.

Marie E. Robert

• Robert ME, Washington MK, Lee JR, Goldenring JR, et al. Rab11a immunohistochemistry does not distinguish between indefinite, low- or high-grade dysplasia in barrett esophagus. Am J Clin Pathol (2005) 124:519-527.
• Robert ME. Celiac Disease and Other Causes of Lymphocytosis in the Small Intestine. In: Rd Odze, ed: Seminars in Diagnostic Pathology: Diagnostic Challenges in Gastrointestinal Pathology. Chapter 4. W.B. Saunders, Philadelphia, PA (2005) 22:284-294.
• Robert ME. The malignant polypectomy specimen: A guide for clinicians. Clinical Gastroenterology and Hepatology. 2006 (in press).

Michael L. Schilsky

• Schilsky, M.L., Tavill, A.S. Wilson’s disease. In: Diseases of the Liver, ed., Schiff, E.R., Sorrell, M.F., Maddrey, W.C., Lippincott-Raven, Philadelphia, PA, 2007
• Fox A, Schilsky M. Once Daily Trientine for Maintenance Therapy of Wilson Disease. Am J Gastroenterol. 2007 In Press.
• Roberts E, Schilsky ML A practice guideline on Wilson disease. Hepatology 2008 in press.

Uzma Siddiqui

• Siddiqui, U. & Dharan, VM & Aslanian, H. (Apr 16 2007). Stomach - Mucosa Associated Lymphoid Tissue. The DAVE Project. Retrieved Apr, 27, 2007, from
  http://dave1.mgh.harvard.edu/ViewFilms.cfm?film_id=592
• Siddiqui U, Bini EJ, Chandarana K, Leong J, Ramsetty S, Schiliro D, Poles M. Prevalence and Impact of Diarrhea on Health-related Quality of Life in HIV-infected Patients in the Era of Highly Active Antiretroviral Therapy. J Clin Gastroenterol. 2007 May-Jun;41(5):484-90.
• Siddiqui U, Proctor D. Flexible sigmoidoscopy and colonoscopy during pregnancy. Gastrointest Endosc Clin N Am. 2006 Jan;16(1):59-69.

Carol J. Soroka

• Boyer, JL, Trauner, M, Mennone, A, Soroka, CJ, Cai, S-Y, Moustafa, T, Zollner, G, Lee, JY and Ballatori, N. Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OSTα-OSTß, in cholestasis in humans and rodents. Am J Physiology 2006 Vol. 290:G1124-G1130
• Ballatori, N, Christian, WV, Lee, J-Y, Dawson, PA, Soroka, CJ, Boyer, JL, Madejczyk, MS and Li, N. OSTα-Ostß: A major basolateral bile acid and steroid transporter in human intestinal, renal and biliary epithelia. Hepatology 2005 Vol 42:1270-1279.
• Ballatori, N, Christian, WV, Lee, J-Y, Dawson, PA, Soroka, CJ, Boyer, JL, Madejczyk, MS and Li, N. OSTα-Ostß: A major basolateral bile acid and steroid transporter in human intestinal, renal and biliary epithelia. Hepatology 2005 Vol 42:1270-1279.

Carlo Spirli

• Fabris L, Cadamuro M, Guido M, Spirli C, Fiorotto R, Colledan M, Torre G, Alberti D, Sonzogni A, Okolicsanyi L, Strazzabosco M. Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling. Am J Pathol. 2007:171(2):641-53.
• Bigler L, Spirli C, Fiorotto R, Pettenazzo A, Duner E, Baritussio A, Follath F, Ha HR. Synthesis and cytotoxicity properties of amiodarone analogues. Eur J Med Chem. 2007:42:861-7
• Fabris L, Cadamuro M, Fiorotto R, Roskams T, Spirli C, Melero S, Sonzogni A, Joplin RE, Okolicsanyi L, Strazzabosco M. Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases. Hepatology. 2006;43:1001-1012.
• Fabris L, Cadamuro M, Libbrecht L, Raynaud P, Spirlì C, Fiorotto R, Okolicsanyi L, Lemaigre FP, Strazzabosco M, Roskams T. Angiogenic Growth Factors Secreted by Liver Epithelial Cells Modulate Arterial Vasculogenesis during Human Liver Development. Hepatology, in press.
• Fiorotto R, Spirli C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M. Ursodeoxicholic acid stimulates cholangiocytes fluid secretion in mice via CFTR-dependent secretion. Gastroenterology, in press.

Mario Strazzabosco

• Melzi ML, Kelly DA, Colombo C, Jara P, Manzanares J, Colledan M, Strazzabosco M, DeLorenzo P, Valsecchi MG, Adam R, Gridelli B, Assael BM; EGSLTCF; European Liver Transplant Association (ELTA); European Cystic Fibrosis Society (ECFS). Liver transplant in cystic fibrosis: a poll among European centers. A study from the European Liver Transplant Registry. Transpl Int. 2006; 19:726-731.
• Corno V, Colledan M, Dezza MC, Guizzetti M, Lucianetti A, Maldini G, Pinelli D, Giovanelli M, Zambelli M, Torre G, Strazzabosco M. Extended right split liver graft for primary transplantation in children and adults. Transpl Int. 2006;19:492-499.
• Fabris L, Cadamuro M, Fiorotto R, Roskams T, Spirli C, Melero S, Sonzogni A, Joplin RE, Okolicsanyi L, Strazzabosco M. Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases. Hepatology. 2006;43:1001-1012.
• Corno V, Dezza MC, Lucianetti A, Codazzi D, Carrara B, Pinelli D, Parigi PC, Guizzetti M, Strazzabosco M, Melzi ML, Gaffuri G, Sonzogni V, Rossi A, Fagiuoli S, Colledan M. Combined double lung-liver transplantation for cystic fibrosis without cardio-pulmonary by-pass. Am J Transplant. 2007;7:2433-2438.
• Taddei TH, Strazzabosco M. Hepatic venous pressure gradient (HVPG), serum sodium (SNa), and model of end-stage liver disease score (MELD): prognostic significance and correlations. J Clin Gastroenterol. 2007;41:641-643.
• Fabris L, Cadamuro M, Guido M, Spirli C, Fiorotto R, Colledan M, Torre G, Alberti D, Sonzogni A, Okolicsanyi L, Strazzabosco M. Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling. Am J Pathol. 2007:171(2):641-53.
• Angelico M, Petrolati A, Lionetti R, Lenci I, Burra P, Donato MF, Merli M, Strazzabosco M, Tisone G. A randomized study on Peg-interferon alfa-2a with or without ribavirin in liver transplant recipients with recurrent hepatitis C. J Hepatol. 2007;46:1009-1017.
• Clementi M, Di Gianantonio E, Fabris L, Forabosco P, Strazzabosco M, Tenconi R, Okolicsanyi L. Inheritance of hyperbilirubinemia: evidence for a major autosomal recessive gene. Dig Liver Dis. 2007;(4):351-355.
• Montalbano M, Pasulo L, Sonzogni A, Remuzzi G, Colledan M, Strazzabosco M. Treatment with pegylated interferon and ribavirin for hepatitis C virus-associated severe cryoglobulinemia in a liver/kidney transplant recipient. J Clin Gastroenterol. 2007;41(2):216-220.
• Strazzabosco M, Fabris L. Functional anatomy of normal bile ducts. Anat Rec A Discov Mol Cell Evol Biol (in press).
• Fabris L*, Cadamuro M*, Libbrecht L, Raynaud P, Spirlì C, Fiorotto R, Okolicsanyi L, Lemaigre FP, Strazzabosco M, Roskams T. Angiogenic Growth Factors Secreted by Liver Epithelial Cells Modulate Arterial Vasculogenesis during Human Liver Development. Hepatology, in press.
• Fiorotto R, Spirli’ C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M. Ursodeoxicholic acid stimulates cholangiocytes fluid secretion in mice via CFTR-dependent secretion. Gastroenterology, in press.

Scott Swenson

• Cirrhosis and portal hypertension (2004). Chap. 45 in Field Guide to Internal Medicine. ES Swenson. Lippincott, Williams and Wilkins, Philadelphia, PA.
• Dose and time-dependent oval cell reaction in acetaminophen-induced murine liver injury (2005). AV Kofman, G Morgan, A Kirschenbaum, J Osbeck, M Hussain, S Swenson and ND Theise. Hepatology 41(6): 1252-126.
• Engraftment of bone marrow derived epithelial cells (2005). JS Van Arnam, E Herzog, J Grove, E Bruscia, E Ziegler, S Swenson, DS Krause. Stem Cell Reviews 1:21-28.
• Limitations of green fluorescent protein (GFP) as a cell lineage marker (2007). ES Swenson, JG Price, T Brazelton, DS Krause. Stem Cells 25: 2593-2600.
• Induced pluripotent cells mimicking human embryonic stem cells. M Mohamadnejad M, ES Swenson (2008). Arch Iran Med. 11:125-8.
• Physiologic variations in stem cell factor and stromal-derived factor-1 in murine models of liver injury and regeneration. ES Swenson, R Kuwahara, DS Krause, ND Theise. In press, Liver International.
• The hepatic stem cell niche: identification by label retaining cell assay. R Kuwahara, AV Kofman, CS Landis, ES Swenson, E Barendswaard, ND Theise ND. In press, Hepatology.

Edwin C. Thrower

• Edwin C. Thrower, Alexander P.E. Diaz de Villalvilla, Thomas R. Kolodecik, and Fred S. Gorelick (2006). Zymogen activation in a reconstituted pancreatic acinar cell system. Am J Physiol Gastrointest Liver Physiol 290: G894-G902
• Gorelick, F.S., Shugrue, C.A., Kolodecik, T.R. and Thrower, E.C. Vacuolar adenosine triphosphatase and pancreatic acinar cell function. J. Gastroenterol Hepatol. (2006) Oct 21 Suppl 3:S18-21.
• Waterford, S.D., Kolodecik, T.R., Thrower, E.C. and Gorelick, F.S. (2005) Vacuolar ATPase regulates zymogen activation in pancreatic acini. J. Biol. Chem. 280, 5430-5434.

Tamar Taddei

• Carmack S, Taddei T, Robert M, Mistry P, Jain D. T-cell sinusoidal lymphocytosis in hepatitis C liver biopsies is increased in patients with mixed cryoglobulinemia. Am J Gastroenterol (in press).
• Taddei T and Strazzabosco M. Hepatic venous pressure gradient (HVPG), serum sodium (SNa), and model of end-stage liver disease score (MELD) – prognostic significance and correlations. Journal of Clinical Gastroenterology. 2007;41(7):641-643.
• Rustgi V, Marino G, Rustgi S, Halpern M, Johnson L, Tolleris C, Taddei T. Impact of body mass index on graft failure and overall survival following liver transplant. Clinical Transplantation. 2004;18(6):634-637.
• Taddei T, Younossi Z. The efficacy of weight reduction in nonalcoholic fatty liver disease. Evidence-Based Gastroenterology. 2004;5(3):96-97.

Jin Yu

• Jin Yu, Elise Lavoie, Nina Sheung, Jean Sevigny, Jonathan A. Dranoff. IL-6 regulates transcription of NTPDase2 via specific promoter elements. (submitted for publication)
• Kruglov E, Correa P, Arora G, Yu J, Dranoff JA. Molecular basis for calcium signaling in hepatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology 2007, 292(4):G975-82
• Bo Ding, Chuan-ju Liu, Yan Huang, Jin Yu, Weihua Kong and Peter Lengyel. p204 protein is overcomes the inhibition of differentiation of p19 murine embryonal carcinoma cells to beating cardiac myocytes by Id proteins. Journal of Biological chemistry, 2006, 281(21):14893-14906