Digestive Diseases
333 Cedar Street
Room 1080 LMP
New Haven, CT 06520-8000
Tel: 203.785.4138
Fax: 203.785.7273
Recent Publications
Clara Abraham
- Hedl M, Li J, Cho JH, and Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. PNAS. Epub Nov 21, 2007.
- Marski M, Ye AL, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints. J Immunol. 178:2104-2112, 2007.
- Abraham C and Cho JH. Bugging of the intestinal mucosa. N Engl J Med. 357:708-710, 2007.
Harry Aslanian
- Aslanian, H. “EUS Guided FNA of a Liver Mass”. The DAVE Project. 12 Dec 2006. Jan 8, 2007 (peer reviewed, online video atlas).
- Savides TJ, Donohue M, Hunt G, Al-Haddad M, Aslanian H, Ben-Menachem T, Chen VK, Coyle W, Deutsch J, DeWitt J, Dhawan M, Eckardt A, Eloubeidi M, Esker A, Gordon SR, Gress F, Ikenberry S, Joyce AM, Klapman J, Lo S, Maluf-Filho F, Nickl N, Singh V, Wills J, Behling C. EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. Gastrointest Endosc 2007;66:277-8.
- Rogart J., Greenwald A., Rossi F., Barrett P., Aslanian H. Aortoesophageal fistula following polyflex stent placement for refractory benign esophageal stricture. Endoscopy (in press).
- Rossi, F., Sosa, JA., Aslanian, HR. Screening colonoscopy and fecal occult blood testing practice patterns: a population based survey of gastroenterologists. Journal of Clinical Gastroenterology (in press).
Henry Binder
- Hoque, K.M., Binder, H.J.: Zinc in the treatment of diarrhea: Current status and assessment. Gastroenterology 130:2201-2205, 2006.
- Subramanya, S, Balakrishnan, BS, Ramakrishna, S, Young, GP, Binder, HJ: Evaluation of oral rehydration solution by whole gut perfusion in rats: effects of osmolarity, sodium concentration and resistant starch. J. Ped. Gastro., Nutr. 43:568-77, 2006.
- Subramanya SB, Rajendran VM, Srinivasan P, Nanda Kumar NS, Ramakrishna BS, Binder HJ. Differential regulation of cholera toxin-inhibited Na-H exchange isoforms by butyrate in rat ileum. Am. J. Physiol. Gastrointest. Liver Physiol. 293:G857-63, 2007.
- Binder, HJ: Causes of chronic diarrhea (Perspectives). New Engl. J. Med. 355:236-239, 2006.
- Barmeyer, C, Ye, JH, Sidani S, Geibel, J, Binder, HJ, Rajendran, VM: Characteristics of rat down-regulated-in-adenoma (rDRA) expressed in HEk 293 cells. Plufgers Arch. 454:41-45, 2007.
- Balakrishnan, BS, Venkataraman, S., Mohen, V., Sebastrian, BK, Gursamy, M, Young, GP, Farthing, MJ, and Binder, HJ: Amylase resistant starch in hypo-osmolar oral rehydration solution for the treatment of acute severe watery diarrhea in adults. PLoS ONE. Feb 13:3: e1587, 2008.
- Petri, Jr., W.A., Miller, M., Binder, H.J., Levine, M.M., Dillingham, R., Guerrant, R.L.: Enteric infections, diarrhea, and their impact on function and development. J. Clin. Gastro. 118:1277-1290, 2008.
- Binder, H.J.: Disorders of absorption. In: Harrison’s Principles of Internal Medicine. Ed. Fauci, A. Kasper, D.L., McGraw Hill, New York. 17th ed. pp 1872-1886, 2008.
- Binder, H.J. Mechanisms of diarrhea in Inflammatory Bowel Diseases. In: Molecular Regulation of Tight Junction Function. Edited by Fromm, M and Schultke, J. Annals of New York Academy of Sciences (in press) 2009.
James Boyer
- Ballatori N, Henson JH, Seward DJ, Cai S-Y, Runnegar M, Fricker G, Miller DS and Boyer JL. Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comp Biochem Physiol B Biochem Mol Biol. 2006 Jun;144(2):167-79
- Mennone, A, Soroka, CJ, Cai, S-Y, Harry, K, Adachi, M, Hagey, L, Schuetz, J and Boyer, JL. Mrp4 -/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology. 2006 May;43(5):1013-21
- Denk, GU, Shi-Ying Cai, Wen-Sheng Chen, Aiping Lin, Carol J.Soroka, James L. Boyer. A comparison of gene expression in mouse liver and kidney in obstructive cholestasis utilizing high-density oligonucleotide microarray technology. World J Gastroenterol. 2006 Apr 28;12(16):2536-48.
- Boyer, JL, Trauner, M, Mennone, A, Soroka, CJ, Cai, S-Y, Moustafa, T, Zollner, G, Lee, JY and Ballatori, N. Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OST -OSTß, in cholestasis in humans and rodents. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1124-30.
- Wang, W, Soroka, CJ, Mennone, A, Rahner, C, Harry, K, Pypaert, M and Boyer, JL. Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Gastroenterology. 131:878-884,2006
- Villanueva SS, Ruiz ML, Soroka CJ, Cai SY, Luquita MG, Torres AM, Sanchez Pozzi EJ, Pellegrino JM, Boyer JL, Catania VA, Mottino AD. Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats. Drug Metab Dispos 34:1301-1309,2006.
- Tradtrantip L, Boyer JL, Suksamrarn A, PIyachaturawat P. Differential effects of hydroxyacetophenone analogues on the transcytotic vesicular pathway in rat liver. Eur. J. Phrm 547:152-159,2006.
- Meier-Abt F, Hammann-Hanni A, Stieger B, Ballatori N and Boyer JL. The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver. Tox. Appl. Pharm. 218:274-279,2007.
- Chen, W. Cai, SY, Xu, S, Denson, L, Soroka, C, Boyer, J. Nuclear Receptors RXR :RAR are Repressors for Human MRP3 Expression, Am J Physiol Gastrointest Liver Physiol. 292(5):G1221-7,2007.
- Tradtrantip,L, Piyachaturawat, P, Soroka, C, Harry, K, Mennone, A, Mahagita, C, Ballatori, N, and Boyer, JL Phloracetophenone-Induced Choleresis in Rat is Mediated Through Mrp2. Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G66-74
- Cai SY, Xiong L, Wray CG, Ballatori N, Boyer JL. The farnesoid X receptor, FXR{alpha}/NR1H4, acquired ligand specificity for bile salts late in vertebrate evolution. Am J Physiol Regul Integr Comp Physiol.. 293(3):R1400-9, 2007
- Sun AQ, Ponamgi VM, Boyer JL, Suchy FJ. Membrane Trafficking of the Human OrganicAnion-Transporting Polypeptide C (hOATPC). Pharm Res. 2007 Jul 20; [Epub ahead of print]
- Lam P, Pearson CL, Soroka C, Xu S, Mennone A, Boyer JL. The Level of Plasma Membrane Expression in Progressive and Benign Mutations of the Bile Salt Export Pump (Bsep/Abcb11) Correlate with Severity of Cholestatic Diseases. Am J Physiol Cell Physiol. 2007 Sep 13; [Epub ahead of print]
Judy H. Cho
- Gewritz ST, Vijay-Kuman M, Brant SR, Duerr RH, Nicolae DL, Cho JH. Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2006; 290: G1157-1163.
- Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee A, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH. A genome-wide association study identified IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-3.
- Cho JH and Weaver CT. Invited review. Inflammatory bowel disease genetics. Gastroenterology. 2007;133:1327-39.
- Yao-Shugart Y, Duerr RH, Brant SR, Rioux JD, Silverberg MS, Taylor KD, Schumm LP, Cho* JH, Brant* SR (*shared senior authors). SNP-based linkage screen identifies a significant locus on chromosome 13p. Genes and Immunity 2008;9:161-7.
- Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Burtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Gargan SR, Xavier R, the NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, the Belgian-French IBD Consortium, the Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ. Genome-wide association defines more than thirty distinct susceptibility loci for Crohn’s disease. Nature Genetics 2008, 40: 955-62.
- McCarroll SA, Huett A, Kuballa P, Chilewski S, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn’s disease. Nature Genetics, August 24, 2008.
- Cho JH. Genetics and immunopathogenesis of inflammatory bowel disease. Nature Reviews Immunology 2008; 8:458-66.
Chuhan Chung
- Ethanol Exposure Depletes Pigment Epithelium-Derived Factor (PEDF), a Novel
Lipid Regulator in the Liver.
Chung C, Shugrue C, Nagar A, Doll JA, Cornwell M, Kolodecik T, Pandol S,
Gorelick FS. Gastroenterology 2008, In Press.
- Anti-angiogenic Pigment Epithelium-Derived Factor Regulates Hepatocytes
Triglyceride Content Through Adipose Triglyceride Lipase (ATGL). Chung C, Doll
JA, Gattu AK, Shugrue C, Cornwell M, Fitchev P, Crawford SE. J Hepatol 2008;
48:471-478.
- Pigment Epithelium-Derived Factor (PEDF) is an Angiogenesis and Lipid Regulator
that Activates Peroxisome Proliferator-Activated Receptor á (PPARá). Chung C,
Doll JA, Stellmach VM, Gonzales J,Surapureddi S, Cornwell M, Reddy JK, Crawford
SE. Adv Exp Med Biol 2008; 617: 591-7.
Jon Dranoff
- Jhandier MN, Kruglov EA, Lavoie EG, Sevigny J, Dranoff JA. Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. J. Biol. Chem. 280:22986 (2005).
- Kruglov EA, Nathanson RA, Nguyen T, Dranoff JA. Secretion of MCP-1/CCL2 by bile duct epithelia induces myofibrobastic transdifferentiation of portal fibroblasts. Am. J. Physiol. 290:G765 (2006).
- Kruglov EA, Correa PR, Arora G, Yu J, Nathanson MH, Dranoff JA. Molecular basis for calcium signaling in hepatic stellate cells. Am. J. Physiol. 292:G975 (2007).
Martin Floch
- Floch, MH, Madsen KK, Jenkins DJ, Guandalini S, Katz JA, Onderdonk A, Walker WA, Fedorak RN, Camillieri M. Recommendations for probiotic use. J Clin Gastroenterol 2006;40(3):275-8
- Siewert JR, Giuli R, Floch MH. OESO and the Journal of Clinical
Gastroenterology. J Clin Gastroenterol 2006;40(5):373
- Floch, MH. A hypothesis: is diverticulitis a type of inflammatory bowel disease?
J Clin Gastroenterol 2006;40(7 Suppl 3):S121-5
- Floch, MH, White JA. Management of diverticular disease is changing. World J
Gastroenterol 2006 May 28;12(20): 3225-3228
- Floch, MH. Report on 8th World Congress of OESO. J Clin Gastroenterol
2007;41(2):121-2
- Park J, Floch MH. Prebiotics, Probiotics, and Dietary Fiber in Gastrointestinal
Disease. In: Gastroenterology Clinics of North America. Philadelphia, PA.
Elsevier March 2007;36(1):47-63
- Binder JH, Floch MH. Enteric Flora in Health and Disease. J Clin Gastroenterol
2007;41(Suppl 1):S1
Guadalupe Garcia-Tsao
- Longacre AV, Garcia-Tsao G. A commonsense approach to esophageal varices. Clin Liver Dis 2006;10:613-625.
- Ghassemi S, Garcia-Tsao G. Prevention and treatment of infections in patients with cirrhosis. Best Pract Res Clin Gastroenterol. 2007;21(1):77-93.
- Garcia-Tsao G. Liver involvement in hereditary hemorrhagic telangiectasia (HHT). J Hepatol. 2007 Mar;46(3):499-507.
Fred Gorelick
- S. Husain, T. Kolodecik, M. Nathanson, F. Gorelick. Regulation of zymogen processing in acinar cells by the ryanodine receptor. Proc Natl Acad Sci, USA. 2005 102:14386-91.
- Thrower, A. Devilla-Villa, T. Kolodecik and F. Gorelick. Zymogen activation in a reconstituted pancreatic acinar cell system. Am J Physiol Gastrointest Liver Physiol. 2006 290(5):G894-90.
- Cai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proc Natl Acad Sci U S A. 2006 103:1941-6.
- Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster
Proc Natl Acad Sci U S A. 2006 103:1936-40.
- Otani T, Matsukura A, Takamoto T, Seyama Y, Shimizu Y, Shinomiya M, Usui H, Gorelick FS, Makuuchi M. Effects of pancreatic duct ligation on pancreatic response to bombesin. Am J Physiol Gastrointest Liver Physiol. 2006 290(4):G633-9.
- Siddiqi SA, Siddiqi S, Mahan J, Peggs K, Gorelick FS, Mansbach CM. The identification of a novel ER to Golgi SNARE complex used by the Pre-chylomicron transport vesicle.J Biol Chem. 2006 281(30):20974-82.
- Siddiqi SA, Mahan J, Siddiqi S, Gorelick FS, Mansbach CM 2nd. Vesicle-associated membrane protein 7 is expressed in intestinal ER.J Cell Sci. 2006 119:943-50.
- Chaudhuri A, Husain SZ, Kolodecik TR, Grant WM, Gorelick F. Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.Am J Physiol Gastrointest Liver Physiol. 2007 292: G1403-G1410.
- Husain SZ, Grant WM, Gorelick F, Nathanson MH, Shah AU. Caerulein-induced Intracellular Pancreatic Zymogen Activation is Dependent upon Calcineurin. Am J Physiol Gastrointest Liver Physiol. 2007 292: G1594-9.
Roberto Groszmann
- Lee CH, Loureiro-Silva MR, Abraldes JG, Iwakiri Y, Haq O, Groszmann RJ. Decreased intrahepatic response to alpha(1)-adrenergic agonists in lipopolysaccharide-treated rats is located in the sinusoidal area and depends on Kupffer cell function. J Gastroenterol Hepatol. 2007 Jun;22(6):893-900. Epub 2007 May 13.
- Qamar AA, Grace ND, Groszmann RJ, Garcia-Tsao G, Bosch J, Burroughs AK, Maurer R, Planas R, Escorsell A, Garcia-Pagan JC, Patch D, Matloff DS, Makuch R; Portal Hypertension Collaborative Group. Platelet count is not a predictor of the presence or development of gastroesophageal varices in cirrhosis. Hepatology. 2008 Jan;47(1):153-9.
- Garcia-Tsao G, Bosch J, and Groszmann, RJ. Portal hypertension and variceal bleeding – Unresolved Issues. Summary of an American Association for the Study of Liver Disease and European Association for the Study of the Liver Single-Topic Conference. Hepatology 2008 May;47(5):1764-1772.
- Lim JK, Groszmann RJ. Vasoconstrictor therapy for the hepatorenal syndrome. Gastroenterology. 2008 May;134(5):1608-11.
- Alexander Zipprich, Mauricio R. Loureiro-Silva, Irita D’Silva, Roberto J. Groszmann. The role of hepatic arterial flow on portal venous and hepatic venous wedged pressure in the isolated perfused CCl4-cirrhotic liver. American Journal of Physiology: Gastrointestinal and Hepatology 2008 July 295(1):G197-G202.
- Alexander Zipprich, Mauricio R. Loureiro-Silva, Dhanpat Jain, Irita D’Silva, Roberto J. Groszmann. Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver. Journal of Hepatology 49(5):739-745; Nov 2008.
- Cristina Ripoll, Roberto Groszmann, Guadalupe Garcia-Tsao, Jaime Bosch, Norman Grace, Andrew Burroughs, Ramon Planas, Angels Escorsell, Juan Carlos Garcia-Pagan, Robert Makuch, David Patch, Daniel S. Matloff, and the Portal Hypertension Collaborative Group. Hepatic Venous Pressure Gradient Predicts Development of Hepatocellular Carcinoma Independent of Severity of Cirrhosis. Journal of Hepatology 2008 “Submitted”
Avlin Imaeda
- Imaeda, A., Sutterwala, F., Watanabe, A., Mahmood, S., Sohail, M., Flavell, R., Mehal, W. (2007, manuscript submitted) Acetaminophen induced hepatotoxicity is dependent on the NALP3 inflammasome and can be inhibited by aspirin.
- Longacre, A., Imaeda, A., Garcia-Tsao, G., Fraenkel, L. (2007) A pilot project examining the predicted preferences of patients an dphysicians in the primary prophylaxis of variceal hemorrhage. Hepatology (published online Oct 12)
- Rodes, J., Benhamou, J-P., Blei, A., Reichen, J., Rizzetto, M. ed Textbook of Hepatology.
Blackwell Publishing (2007). “Chap 2.7.3 Antibody Production and Transport in the
Liver.” Imaeda, A, Mehal, W. pp325-332
Yasuko Iwakiri
- Loureiro-Silva, M.R., Iwakiri,Y., Haq, O., and Groszmann, R.J. Phosphodiesterase-5 (PDE-5) is up-regulated in cirrhotic rat livers; potential role for PDE-5 inhibitors in reducing the increased intrahepatic vascular tone in cirrhosis. J Hepatology. 2006; 44(5): 886-93.
- Abraldes, J.G. *, Iwakiri, Y. *, Loureiro-Silva, M., Haq, O., Sessa, W.C., and Groszmann, R.J. Mild increases in portal pressure upregulate VEGF and eNOS in the intestinal microcirculatory bed leading to the hyperdynamic state. Am J Physiol. Liver and Gastro. 2006; 290(5):G980-7.* Sharing first authorship.
- Iwakiri, Y. and Groszmann, R.J. The Hyperdynamic Circulation of Chronic Liver Diseases: From the Patient to the Molecule. Hepatology. 2006: S121-31.
- Iwakiri, Y., Satoh, A., Chatterjee, S., Shah, V., Chalouni, C., Toomre, D., Fulton, D., Groszmann, R.J., and Sessa. W.C. Nitric Oxide Synthase Establishes a Local Nitric Oxide Gradient Regulating S-nitrosylation and Protein Secretion. Proc Natl Acad Sci USA. 2006; 103(52): 19777-82.
- Kwon, S., Groszmann, R.J., and Iwakiri, Y (corresponding). Increased Neuronal Nitric Oxide Synthase Interaction with Soluble Guanylate Cyclase Contributes to the Splanchnic Arterial Vasodilation in Portal Hypertensive Rats. Hepatology Research. 2007; 37(1): 58-67.
- Lee, C.H., Loureiro-Silva, M.R., Abraldes, J.G., Iwakiri, Y., Haq, O., and Groszmann, R.J. Decreased intrahepatic response to alpha(1)-adrenergic agonists in lipopolysaccharide-treated rats is located in the sinusoidal area and depends on Kupffer cell function. J Gastroenterol Hepatol 2007; 22(6): 893-900.
- Iwakiri, Y. and Groszmann, R.J. Vascular Endothelial Dysfunction in Cirrhosis. Journal of Hepatology. 2007; 46(5): 927-934.
- Iwakiri, Y. The molecules: Mechanisms of arterial vasodilatation observed in the splanchnic and systemic circulation in portal hypertension. J Clin Gastroenterol. 2007; 41(10 Suppl 3): S288-294.
- Fernández-Hernando, C., Ackah, E., Yu, J., Suárez, J., Murata, T., Iwakiri, Y., Prendergast, J., Miao, R. Q., Birnbaum, M. J., and Sessa, W. C. Loss of Akt1 leads to severe atherosclerosis and occlusive proximal coronary artery disease: Evidence for a dominant role of vascular Akt1 in atheroprotection. Cell Metabolism. 2007; 6(6):446-457.
- Iwakiri, Y., Grisham, M., and Shah, V. Vascular Biology and Pathobiology of the Liver: Report of a Single Topic Symposium. Hepatology. 2008; 47(5): 1754-63.
Dhanpat Jain
- Jain D, Fatima Eslami-Varzaneh,MD* ; Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite Glandular and Endocrine Tumors of the Stomach with Pancreatic Acinar Differentiation. Am J Surg Pathol, 2005, 29:1524-29.
- Marginean EC, M Bennick M, Cycyzk J, Robert ME, Jain D. Gastric Glandular Siderosis: Patterns and significance. Am J Surg Pathol, 30:514-520, 2006.
- Nagula S, Jain D, Groszmann RJ, Garcia-Tsao L. Histological-hemodynamic correlation in cirrhosis – A histological classification of the severity of cirrhosis. J Hepatology, 44;111-117, 2006.
Sofia Simona Jakab
- Jakab SS, Navarro VJ, Colombe BW, Daskalakis C, Herrine SK, Rossi S. The Impact of HLA Match on Living-Donor Liver Transplantation Outcomes: An Analysis of the United Network for Organ Sharing Database. Liver Transplantation. 2007 Oct;13(10): 1405-13.
- Jakab SS, West AB, Meighan DM, Brown RS Jr, Hale WB. Mycophenolate Mofetil for Drug-Induced Vanishing Bile Duct Syndrome. World J Gastroenterol. 2007 Dec 7;13(45):6087-9.
- Jakab SS, Mitroo P, Rubin R, Herrine SK, Navarro VJ. Extensive Intrahepatic Cholelithiasis with Large Biliary Abscesses. Poster presentation, ACG National Fellows Forum, Reston, VA, June 2006.
- Jakab SS, Clayton M, Herrine SK, Navarro VJ, Feitelson M. Expression of HBx-Regulated Genes Is Not Limited To HBV-Related Hepatocellular Carcinoma. Oral presentation, Komarov Competition, Philadelphia, March 2006.
- Gaglio PJ, Jakab SS, Novogrudsky A, Emond JC, Lefkowitch J, Brown RS Jr. Hepatitis C Recurrence Following Liver Transplantation: Does Histologic Severity of Inflammation in the Explant Correlate with Recurrence? Poster presentation, 2004 American Transplant Congress, Boston, MA.
Priya Jamidar
- Vignesh S, Jamidar P. EUS-guided pancreatogastrostomy and pancreatobulbostomy in patients with pancreatic-duct obstruction inaccessible to transpapillary endoscopic therapy: working our way to NOTES. Gastrointest Endosc. 2007 Feb;65(2):242-6.
- Siddiqui UD, Jamidar PA. Endoscopic therapy for the treatment of pain in chronic pancreatitis: a success story in tropical pancreatitis. Gastrointest Endosc. 2007 Jul;66(1):76-8.
- Aslanian H, Nagar A, Jamidar P. Diseases of the Pancreas. In: Chang EB, Kuemmerle JF, eds. DDSP Version 5.0: A Core Curriculum and Self- Assessment in Gastroenterology and Hepatology. 5th ed. Dubuque, IA: Kendall/Hunt; 2007:145-175.
- Vargo JJ, Ahmad AS, Aslanian HR, Buscaglia JM, Das AM, Desilets DJ, Dunkin BJ, Inkster M, Jamidar PA, Kowalski TE, Marks JM, McHenry L Jr, Mishra G, Petrini JL, Pfau PR, Savides TA. Training in patient monitoring and sedation and analgesia. Gastrointest Endosc. 2007 Jul;66(1):7-10.
- Roberts KE, Panait L, Duffy, AJ, Jamidar PA, Bell RL. Laparoscopic-Assisted Transgastric Endoscopy: Current Indications and Future Implications. J Soc Laparoendosc Surg 2008; 12:30-36
- Jamidar PA, Cadeddu M, Mosse A, Boyd, M and Swain, P (May 19, 2008). Billiary-Choledocho-Duodenostomy Using a Magnetic Compression Device. The DAVE Project. Retrieved Aug 6, 2008 from http://daveproject.org/
- Rogart JN, Boghos A, Rossi F, Al-Hashem H, Siddiqui UD, Jamidar P, Aslanian H. Analysis of endoscopic management of occluded metal biliary stents at a single tertiary care center. Gastrointestinal Endoscopy (In Press, accepted 3/11/08).
- Rogart JN, Jain D, Siddiqui UD, Oren T, Lim J, Jamidar P, Aslanian H. Narrow band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experience. Gastrointestinal Endoscopy (In Press, accepted 4/21/08).
- Rogart JN, Siddiqui UD, Jamidar PA, Aslanian HR. Fellow participation may increase adenoma detection rate during colonoscopy. American Journal of Gastroenterology (In Press, accepted 6/5/08).
- Al-Hashem H, Muralidharan V, Hartley C, Jamidar P. Biliary disease in pregnancy with an emphasis on the role of ERCP. (In Press, Accepted 7/17/08), Journal of Clinical Gastroenterology.
- Jamidar P, Cadeddu M, Mosse CA, Swain, P. Hinged Metallo-Plastic Anastomotic Device; A novel method for choledochoduodenostomy. (In Press, Accepted 9/26/08), Gastrointestinal Endoscopy).
- Hagen M, Wagner O, Swain P, Pugin, F, Buchs N, Cadeddu M, Jamidar P, Fasel J, Morel P. Hybrid Natural Orifice Translumenal Endoscopic Surgery (NOTESTM) for Roux-en-Y gastric bypass: An experimental surgical study in human cadavers. (In Press, Accepted 9/29/08), Endoscopy.
Wajahat Mehal
- Lakhani1 SA, Masud1 A, Kuida K, Porter Jr GA, Booth CJ, Mehal WZ, Inayat I, Flavell RA. Caspases 3 and 7: Key Mediators of Mitochon Events of Apoptosis Science. 2006; 311(5762): 847-51.
- Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, and Flavell RA. Modulation of Cell Adhesion and Motility in the Immune System by Myo1f. Science 6, 2006: 136-139
- Badu A, Jha MK, Matza D, Mehal WZ, Freichel M, Flockerzi V, Flavell RA. Critical role for the regulatory subunits of Cav channels in T lymphocyte function. PNAS. 103(42):15529-34, 2006.
- Qamar A, Sheikh SZ, Masud A, Jhandier MN, Inayat IB, Hakim W, Mehal W. In-vitro and In-vivo Protection of Stellate Cells From Apoptosis by Leptin. Digestive Diseases and Sciences. 51(10):1697-705, 2006.
- Hashmi A, Hakim H, Kruglov E, Watanabe A, Watkins W, Dranoff JA,. Mehal WZ. Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells. American Journal of Physiology. 292(1):G395-401, 2007.
- Azuma Watanabe, Ardeshir Hashmi, Wyel Hakim, Dawidson Gomes, Wajahat Mehal DNA from Apoptotic Hepatocytes Induces HSC Differentiation and Inhibits Chemotaxis via TLR9. Hepatology. In Press
- Wyel Hakim, Shehzad Sheikh, Irteza Inayat, Margaret Bia, Cary Caldwell, Dhanpat Jain, Douglas Smith, Amy Friedman, Marc Lorber, Richard Formica, Wajahat Mehal. Pilot study of HCV Response in Patients with End Stage Renal Disease treated with Combination Pegylated Interferon a-2a and Ribavirin. Nephrology Dialysis Transplantation Submitted.
- Mehal WZ. Activation induced cell death (AICD) of hepatic stellate cells. In press with Gastroenterology for Feb 2006.
- Imaeda A., Mehal WZ. The humoral immune response in the liver. 3rd edition of Textbook of Hepatology: From Basic Science to Clinical Practice. Blackwell Publishers, Oxford England.
- Mehal WZ. Intrahepatic lymphocytes. 3rd edition of Textbook of Hepatology: From Basic Science to Clinical Practice. Blackwell Publishers, Oxford England.
Anil Bernard Nagar
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- AGA Gastroenterlogy Teaching project. Pancreatic Physiology and Pancreatitis 2006. Senior Author Fred Gorelick. Co-authors Anil Nagar, Lars Fisher, Mark Topazian, Guillermo Robles-Diaz, Akihiko Sato and Stephen Pandol.
Michael Nathanson
- O’Brien, E.M., Gomes, D.A., Sehgal, S., and Nathanson, M.H.: Hormonal regulation of nuclear permeability. J. Biol. Chem. 282:4210-4217, 2007. (JBC “paper of the week”)
- Hernandez, E., Leite, M.F., Guerra, M.T., Kruglov, E.A., Bruna-Romero, O., Rodrigues, M.A., Gomes, D.A., Giordano, F.J., Dranoff, J.A., and Nathanson, M.H.: The spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves. J. Biol. Chem. 282:10057-10067, 2007.
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- Husain, S.Z., Grant, W., Gorelick, F.S., Nathanson, M.H., and Shah, A.: Caerulein-induced Intracellular Pancreatic Zymogen Activation is Dependent upon Calcineurin. Amer. J. Physiol. 292:G1594-G1599, 2007.
- Rodrigues, M.A., Gomes, D.A., Grant, W., Leite, M.F., Bennett, A.M., Zhang, L., Lam, W., Cheng, Y.-C., and Nathanson, M.H.: Nucleoplasmic calcium regulates cell growth. J. Biol. Chem. 282:17061-17068, 2007.
- Correa, P.R.A.V., Kruglov, E.A., Thompson, M., Leite, M.F., Dranoff, J.A., and Nathanson, M.H.: Succinate is a paracrine signal for liver damage. J. Hepatol. 47:262-269, 2007.
- Nagata, J., Guerra, M.T., Shugrue, C.A., Gomes, D.A., and Nathanson, M.H.: Lipid rafts establish calcium waves in hepatocytes. Gastroenterology 133:256-267, 2007.
- Minagawa, N., Nagata, J., Shibao, K., Masyuk, A.I., Gomes, D.A., Kaunitz, J.D., LeSage, G., Ehrlich, B.E., LaRusso, N.F., and Nathanson, M.H.: Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology 133:1592-1602, 2007. (Featured on the cover)
- Rogart, J.N., Nagata, J., Loeser, C.S., Roorda, R.D., Aslanian, H., Robert, M.E., Zipfel, W.R., and Nathanson, M.H.: Multiphoton imaging can be used for microscopic examination of intact gastrointestinal mucosa. Clinical Gastroenterology and Hepatology 6:95-101, 2008. (Featured on the cover)
- Gomes, D.A., Rodrigues, M.A., Leite, M.F., Gomez, M.V., Varnai, P., Balla, T., Bennett, A.M., and Nathanson, M.H.: c-Met must translocate to the nucleus to initiate Ca2+ signals. J. Biol. Chem. 283:4344-4351, 2008. (JBC “paper of the week”)
- Rodrigues, M.A., Gomes, D.A., Leite, M.F., and Nathanson, M.H.: Insulin induces calcium signals in the nucleus of rat hepatocytes. Hepatology, in press. (Featured on the cover)
Ioannis Oikonomou
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Deborah Proctor
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Marie E. Robert
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Michael L. Schilsky
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Anish Sheth
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Uzma Siddiqui
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Carol J. Soroka
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Carlo Spirli
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Mario Strazzabosco
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Scott Swenson
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- Engraftment of bone marrow derived epithelial cells (2005). JS Van Arnam, E Herzog, J Grove, E Bruscia, E Ziegler, S Swenson, DS Krause. Stem Cell Reviews 1:21-28.
- Limitations of green fluorescent protein (GFP) as a cell lineage marker (2007). ES Swenson, JG Price, T Brazelton, DS Krause. Stem Cells 25: 2593-2600.
- Induced pluripotent cells mimicking human embryonic stem cells. M Mohamadnejad M, ES Swenson (2008). Arch Iran Med. 11:125-8.
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Tamar Taddei
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Edwin C. Thrower
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Jin Yu
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- Jin Yu, Elise Lavoie, Nina Sheung, Jean Sevigny, Jonathan A. Dranoff. IL-6 regulates transcription of NTPDase2 via specific promoter elements. (submitted for publication)